• Users Online: 1108
  • Home
  • Print this page
  • Email this page
Home Current issue Ahead of print Search About us Abstracting and Indexing Editorial board Archives Submit article Instructions Subscribe Contacts Login 
Year : 2010  |  Volume : 5  |  Issue : 3  |  Page : 182-187

Optic Neuritis

Neuro-Ophthalmology Service, Baylor College of Medicine, Houston, Texas, USA

Correspondence Address:
Mary Caitlin Dooley
Neuro-Ophthalmology Service, Baylor College of Medicine, 7200B Cambridge St., Houston, TX 77030
Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and PermissionsRights and Permissions

Demyelinating optic neuritis is the most common cause of unilateral painful visual loss in the United States. Although patients presenting with demyelinating optic neuritis have favorable long-term visual prognosis, optic neuritis is the initial clinical manifestation of multiple sclerosis in 20% of patients. The Optic Neuritis Treatment Trial (ONTT) has helped stratify the risk of developing multiple sclerosis after the first episode of optic neuritis based on abnormal findings on brain MRI. The ONTT also demonstrated that while initial treatment of optic neuritis with intravenous corticosteroids followed by an oral taper accelerates visual recovery, its use does not improve long-term visual outcomes. Long-term treatment with immunomodulating agents such as interferons has been shown to improve clinical outcomes and neuroimaging abnormalities in multiple sclerosis; furthermore interferon use has been associated with decreased risk of subsequent multiple sclerosis in patients with an acute neurologic syndrome. However, several questions regarding the presentation, management, and implications of acute demyelinating optic neuritis remain unanswered.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded82    
    Comments [Add]    

Recommend this journal