Figure 2. Illustration of eye development from the neural plate. The neural plate folds and bulges to give rise to two optic vesicles, each of which will become an eye. The development of one eye from one of the optic vesicles is depicted here. (a) The neuroepithelium of the optic vesicle merges with the invaginating surface ectoderm, leading to induction of the lens placode. (b) The optic vesicle invaginates and the inner layer becomes the bilayered optic cup. The lens placode begins to form the lens vesicle. (c) The optic cup gives rise to the neural retina and the outer layer gives rise to the retinal pigmented epithelium (RPE). The mature eye structure with photoreceptors, interneurons, and ganglion cells is depicted. From Ali and Sowden; copyright license obtained.